The Ebola Outbreak (Episode: "Lisa's Sax", 1997)

The Simpsons has earned quite the reputation for seemingly predicting the future. It’s actually a bit of a meme at this point, with fans pointing out how many things in the real world appear to have been "predicted" by the show, sometimes years in advance. While some of these predictions are purely coincidental or the result of broad satire, others do seem oddly prescient.

The Ebola Outbreak (Episode: "Lisa's Sax", 1997)

• What happened: In the episode, Marge and Homer read a headline that says, "Ebola Virus Threatens Planet."
• Reality: The Ebola outbreak in West Africa began in 2014, nearly two decades after this episode aired.